Data di Pubblicazione:
2011
Abstract:
IL-18 is produced by many cell types, such as Kupffer cells, keratinocytes, macrophages, dendritic cells, and activated T cells stimulated by LPS. It is an important regulator of both innate and acquired immune responses. IL-18 plays a central role in rheumatoid arthritis because of the T cells and macrophages that invade the synovial fluid. These finding support a role for IL-18 in inflammation, allergy and immune diseases.
Tipologia CRIS:
1.1 Articolo in rivista
Keywords:
Autoimmunity, Immunoregulation, Inflammation, Interleukin-18, Lymphocytes
Elenco autori:
Tripodi, Domenico; Anogeianaki, Antonia; Castellani, Maria Luisa; Felaco, Paolo; Toniato, Elena; DE LUTIIS, Maria Anna; Fulcheri, Mario; Tete', Stefano; Salini, Vincenzo; Frydas, I; Sabatino, Giuseppe; Shaik Dasthagirisaheb, Y. B.
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