Oligonucleotidic sequences able to silence the expression of the CYCLIN D1-TROP2 chimera and uses thereof in medical field (United States Patent)
Patent
Publication Date:
2009
abstract:
The invention concerns RNA oligonucleotide sequences or sequences that are transcribed into RNA or analogous molecules able to silence the expression of the CYCLINDl/TROP2 chimeric mRNA and their use in the treatment and the prevention of tumors.
Iris type:
6.1 Brevetto
Keywords:
TROP2, Cyclin D1, chimeric mRNA, siRNA, anticancer therapy
List of contributors: