Use of Trop-2 as predictive marker of response to anti-tumor therapy based on inhibitors of AKT (European Patent)
Patent
Publication Date:
2013
abstract:
The present invention relates to anticancer therapy in patients bearing tumors overexpressing Trop-2, by means of drugs directed against a component of the signalling network of Trop-2, wherein said component is Akt. Trop-2 overexpression can also be exploited for the screening in vitro and in vivo of the anticancer activity of new compounds.
Iris type:
6.1 Brevetto
Keywords:
Trop-2, AKT inhibitors, siRNAs, pharmacological inhibitors, anticancer therapy
List of contributors: