Hitologic and histomorphometric evaluation of extraction sockets: prf vs bio-oss

Aim. Today, implant therapy can be considered predictable, but the mechanisms by which implants are anchored in peri-implant bone are not fully understood. The use of Platelet-Rich Fibrin (PRF) facilitates the processes of post-surgical wound healing by accelerating both the integration and remodeling of bone. PRF contains a significantly higher amount of platelet cytokines, which are harnessed within the mesh of the product. The objective of this study was to evaluate the most appropriate procedure for improving and accelerating the healing process and to optimize the performance of prosthetic therapy in terms of predictability, durability and speed of functionalization, by comparing the histological and histomorphometric of bone regeneration achieved by using PRF and Bio-Oss ®. Methods. We examined two sites after extraction, one of which was treated with Bio-Oss and membrane and the second with PRF and membrane. Four mouths later a core of tissue was harvested in the regenerated area. Both sites were subjected to histological and histomorphometric examination and the Bone Volume (BV) was calculated. Results. From these preliminary assessments it appears that the use of PRF accelerates and improves the quality of bone healing. Conclusions. Our results allows us to test post-extraction implants and to confirm its effectiveness.