COFM10 - PHYSICAL ORGANIC CHEMISTRY AND PHYSICAL METHODS IN ORGANIC CHEMISTRY

The treatment of the linear relations of free energy aims to introduce the student, on a rigorous basis, to the correlations structure-biological activity. In fact, these relationships have proved to be of fundamental importance in the research and development of new substances that are famacologically active. The practical applications of thermodynamics and kinetics to various aspects of organic chemistry, the study of the methods that allow to go back to the mechanism of reactions and the evaluation of the most appropriate solvent and catalyst allow the student to form a cultural baggage essential for the graduate in CTF
The techniques of nuclear magnetic resonance, mass spectrometry and IR spectrophotometry are the fundamental baggage for those who need to determine the structure of organic compounds. The knowledge of these techniques is therefore essential for the graduate in C.T.F., and the course aims to provide him with sufficient theoretical bases for the understanding of NMR, IR and MS spectra, especially as regards the complex theoretical aspects related to nuclear magnetic resonance. Another formative objective of the course is to provide the student with a first practical knowledge of the procedures and experimental approaches for the correct analysis of spectroscopic data that can be obtained in the process of elucidation of the structures of organic molecules.