IB012B - PRINCIPLES OF PHARMACOLOGY AND DRUG DELIVERY

courses
ID:
IB012B
Duration (hours):
30
CFU:
3
SSD:
FARMACOLOGIA
Located in:
PESCARA
Url:
BIOMEDICAL ENGINEERING/MATERIALI E TECNOLOGIE PER LA BIOMEDICINA Year: 2
Year:
2025
Course Catalogue:
https://unich.coursecatalogue.cineca.it/af/2025?co...

Overview

Date/time interval

Primo Semestre (22/09/2025 - 21/12/2025)

Syllabus

Course Objectives

EDUCATIONAL OBJECTIVES
The teaching is part of the specific objectives of the Course of Study aimed at training a professional figure able to know and understand: i) the principles of pharmacokinetics (the pathway of the drug within the human body, evaluated in its qualitative/quantitative aspects) and pharmacodynamics (drug/target interactions and analysis of the dose-response relationship); ii) the main factors responsible for the variability in the response to drugs; iii) what are the molecular targets of the drug; iv) the progress of pharmacology in the production of biotechnological drugs v) the advanced systems developed and used for the controlled release of drugs.
EXPECTED LEARNING OUTCOMES
At the end of the course the student will be able to: i) know the pharmacological basis of therapy; ii) become familiar with innovative strategies aimed at modifying both the pharmacokinetics of drugs and their selectivity to the target organ.
The course will help to provide students with tools that will enable them to: i) enhance their ability to relate in inter and multidisciplinary teams with other professionals (engineers, chemists, pharmaceutical technicians) called upon to research, design and develop a wide variety of biomedical materials, procedures, instruments and equipment; ii) contribute to the progress of medical sciences through the application of engineering disciplines.

Course Prerequisites

As provided for in the teaching regulations.

Teaching Methods

The course includes lectures and interactive lessons.
The course aims to provide the theoretical basis necessary for a reasoned understanding of what the drug produces once it has been introduced into the human body (pharmacodynamics) considering how it is distributed and modified in the body (pharmacokinetics). At the same time, particular attention will be paid to biotechnological approaches used for drug delivery and delivery and to provide the basis for understanding new biotechnological methodologies used in gene therapy.

Assessment Methods

Learning will be assessed by means of a final examination, which consists of an oral test aimed at providing a balanced evaluation of the achievement of the Core Curriculum objectives.
The mode of examination and its evaluation will be indicated by the lecturer at the beginning of the lessons.
Module assessment: Mark in thirtieths.

Texts

The recommended textbooks are:
- Fumagalli - Clementi - AAVV-2016. General and Molecular Pharmacology.
- Goodman & Gilman "The pharmacological bases of therapy. The Manual" 2nd Edition Zanichelli
- "Pharmacology. Basic principles and therapeutic applications" E. Rossi, V. Cuomo, C. Riccardi. 2nd Edition Minerva Medica.
-Crommelin and Sinderal, “Pharmaceutical Biotechnology”Taylor & Francis Group.
- Design of controlled release drug delivery systems / [edited by] Xiaoling Li, Bhaskara R. Jasti. Editore: New York [etc.] : McGraw-Hill,
2006.

Other important tools for the individual preparation are represented by the consultation of "Medline" and of some Journals of high scientific level and of pharmacological and pharmacological-clinical interest. Specific bibliographical indications may be provided during the course.

Contents

The course includes two sections:
1) General Pharmacology: in this section, the principles underlying drug-human organism interactions are described: i) Pharmacodynamics (the cellular and molecular mechanisms underlying the therapeutic, undesirable, and toxic effects of drugs).
ii) Pharmacokinetics (the effects that the body exerts on drugs); iii) the different types of drug delivery and their applications; iv) pharmacogenetics and the variability factors of response to drugs.
2) Special Pharmacology: this section describes the characteristics of the main biotechnological drugs in use and their applicability. In addition, the main pharmacological treatments related to implants are described.

Course Language

Italian

More information

She receives students on Mondays from 3pm to 6pm by appointment to be arranged by email: s.tacconelli@unich.it

Degrees

Degrees

BIOMEDICAL ENGINEERING 
Master’s Degree
2 years
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