ASL 3.0 T perfusion studies

Perfusion refers to the delivery of oxygen, glucose and other nutrients to tissues by means of blood flow and its disruption is commonly reported in different pathologies. In particular, changes in brain perfusion is found in most brain diseases, ranging from stroke to neurodegenerative and neoplastic disorders. In this chapter the basic physics and physiological principles of Arterial Spin Labeling (ASL) brain perfusion measurement are discussed, together with research and clinical applications of this promising noninvasive technique.