Data di Pubblicazione:
2019
Abstract:
The present invention relates to a special type of non-internalizing binding moiety- drug-conjugates that specifically target LGALS3BP. From one aspect, the invention relates to an antibody-drug-conjugate comprising an antibody capable of binding to LGALS3BP, said antibody being conjugated to cytotoxic drugs. The invention also comprises methods of the treatment of LGALS3BP-expressing cancer, including administering to a patient the disclosed drug conjugates and pharmaceutical preparations.
Tipologia CRIS:
6.1 Brevetto
Elenco autori:
Capone, Emily; Giansanti, Francesco; Ippoliti, Rodolfo; Gentile, Roberta; Iacobelli, Stefano; Piccolo, Enza; Ponziani, Sara; Sala, Gianluca
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