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  1. Pubblicazioni

Cardiovascular Risk in Childhood Cancer Survivors

Recensione
Data di Pubblicazione:
2022
Abstract:
Cancer is a prominent cause of death worldwide in the pediatric population. Since childhood cancer is not possible to prevent, it is essential to focus on a prompt and correct diagnosis followed by effective, evidence-based therapy with individualized supportive care. Given the enhancement of childhood cancer management over the past decades, survival rate has significantly improved, thus leading to the progression of several late effects, including metabolic derangements. These metabolic imbalances are associated with the underlying disease and the cancer treatments. As a result, the metabolic state may contribute to a high risk of cardiovascular morbidity and premature mortality among childhood cancer survivors. This review aims to summarize the potential pathophysiological mechanisms linked to the risk of diabetes and metabolic syndrome and screening recommendations. Further investigations are needed to clarify the underlying mechanisms of such metabolic abnormalities and to improve long-term cardiometabolic survival among these patients.
Tipologia CRIS:
1.2 Recensione in rivista
Keywords:
abdominal radiation; chemotherapy; childhood cancer survivors; diabetes; dyslipidemia; hypertension; insulin resistance; metabolic derangements; metabolic syndrome
Elenco autori:
Mainieri, Francesca; Giannini, Cosimo; Chiarelli, Francesco
Autori di Ateneo:
CHIARELLI Francesco
GIANNINI COSIMO
Link alla scheda completa:
https://ricerca.unich.it/handle/11564/800676
Link al Full Text:
https://ricerca.unich.it//retrieve/handle/11564/800676.2/361576/biomedicines-10-03098%20-%20cardiovascular%20risk%20in%20childhood%20cancer....pdf
Pubblicato in:
BIOMEDICINES
Journal
  • Dati Generali

Dati Generali

URL

https://www.mdpi.com/2227-9059/10/12/3098
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