Environmental factors in cancer etiology:
Study of the role of infectious agents and lifestyle factors in carcinogenesis, including Helicobacter pylori virulence in gastric cancer, dietary influences on colorectal mutagenesis, and the interaction between reproductive and genetic factors in breast cancer risk.
Head and Neck Paragangliomas (HNPGL):
Investigation of etiopathogenesis and tumor development, with a focus on genetic and epigenetic mechanisms. Development of preclinical models to study histo- and organogenetic processes. Establishment of a unique collection of over 200 rare neuroendocrine tumor cases.
Metabolomics of Paragangliomas:
Identification of distinct plasma metabolic profiles in paraganglioma patients, with potential applications in diagnosis and disease monitoring, including minimally invasive approaches (e.g., dried blood spot analysis).